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1.
Semergen ; 50(5): 102191, 2024 Feb 02.
Artigo em Inglês | MEDLINE | ID: mdl-38309199

RESUMO

BACKGROUND: During the last years, lifestyle has worsened along the entire European population, causing an alarming boom-up regarding overweight and obese people. Pediatric population is also influenced in this sense, which may predispose to suffer from several diseases in adulthood. Educational interventions at early ages could be an effective strategy to face this situation. AIM: To describe the impact of an educational intervention about healthy lifestyle in adolescents. METHODS: A quasi-experimental study analyzing the knowledge of high school students, before and after a brief educational intervention based on a self-elaborated questionnaire including questions from the validated questionnaire CAPA (from Spanish, Conocimientos en Alimentación de Personas Adolescentes). RESULTS: The results of this study show a significant increase in knowledge about healthy lifestyles in the study population after the educational intervention (14.3±3.8 vs. 16.5±4.5; p<0.001). In addition, this improvement presents an asymmetric distribution according to gender (13.2±3.6 vs. 14.9±4.6; p=0.002 in men; 15.6±3 vs. 18.1±3.6; p<0.001 in women) and the type of educational center (14.17±3.6 vs. 16.48±4.17; p<0.001 in public schools and 14.86±4.15 vs. 16.54±5.32; p=0.047 in private schools). Parents' educational level was associated with improvement in knowledge about healthy lifestyles (13.44±2.9 vs. 15.67±5.37; p=0.132 at low level, 14.22±3.42 vs. 16.9±4.68; p<0.001 at medium level and 15.75±3.3 vs. 17.39±4.5; p=0.022 at high level). CONCLUSION: Educational intervention taught by primary health care professionals is a useful and efficient tool for the acquisition of nutritional and healthy lifestyle knowledge in adolescents.

2.
Rev. clín. esp. (Ed. impr.) ; 223(8): 479-485, oct. 2023. tab
Artigo em Espanhol | IBECS | ID: ibc-225873

RESUMO

Introducción y objetivo La N-acetilcisteína se ha propuesto para el tratamiento de COVID-19 gracias a sus efectos mucolítico, antioxidante y antiinflamatorio. El presente estudio tiene como objetivo evaluar su efecto en pacientes ingresados con COVID-19, en términos de mortalidad. Material y métodos Estudio de cohorte retrospectivo unicéntrico. Se incluyeron todos los pacientes ingresados por COVD-19 entre marzo y abril de 2020 en nuestro hospital. Resultados Un total de 378 pacientes fueron incluidos; de ellos, 196 (51,9%) fueron hombres, la edad media fue de 73,3±14,5 años. Un total de 199 (52,6%) pacientes recibieron tratamiento con N-acetilcisteína. Más del 70% tuvieron tos, fiebre y/o disnea. La mortalidad hospitalaria global fue del 26,7%. Un análisis multivariante mediante regresión logística identificó la edad de los pacientes [mayores de 80 años; OR: 8,4 (IC95%: 3-23,4)], una afectación radiológica moderada o grave medida por la escala RALE [OR: 7,3 (IC95%: 3,2-16,9)], el consumo de tabaco [OR: 2,8 (IC95%: 1,3-6,1)] y arritmia previa [OR: 2,8 (IC95%: 1,3-6,2)] como factores de riesgo que se asociaron independientemente con la mortalidad durante el ingreso. El tratamiento con N-acetilcisteína fue identificado como factor protector [OR: 0,57 (IC95%: 0,31-0,99)]. El asma podría representar asimismo un factor protector de mortalidad, aunque en el presente estudio no alcanza significación estadística [OR: 0,19 (IC95%: 0,03-1,06)]. Conclusiones Los pacientes con COVID-19 tratados con N-acetilcisteína presentaron una menor mortalidad y mejor evolución en nuestro estudio. Futuros estudios prospectivos o ensayos clínicos aleatorizados deben confirmar el papel de la N-acetilcisteína en pacientes con COVID-19 (AU)


Introduction and aim N-acetylcysteine has been proposed for the treatment of COVID-19 thanks to its mucolytic, antioxidant and anti-inflammatory effects. Our aim is to evaluate its effect on patients admitted with COVID-19 in mortality terms. Material and methods Retrospective single-center cohort study. All patients admitted to our hospital for COVID-19 from March to April 2020 have been considered. Results A total of 378 patients were included, being 196 (51.9%) men, with an average age of 73.3±14.5 years. The 52.6% (199) received treatment with N-acetylcysteine. More than 70% presented coughs, fever, and/or dyspnea. The global hospital mortality was 26.7%. A multivariate analysis through logistic regression identified the age of patients [older than 80; OR: 8.4 (95% CI: 3–23.4)], a moderate or severe radiologic affectation measured by the RALE score [OR: 7.3 (95% CI: 3.2–16.9)], the tobacco consumption [OR: 2.8 (95% CI: 1.3–6.1)] and previous arrhythmia [OR 2.8 (95% CI: 1.3–6.2)] as risk factor that were independently associated with mortality during the admission. The treatment with N-acetylcysteine was identified as a protective factor [OR: 0.57 (95% CI: 0.31–0.99)]. Asthma also seems to have a certain protective factor although it was not statistically significant in our study [OR: 0.19 (95% CI: 0.03–1.06)]. Conclusions Patients with COVID-19 treated with N-acetylcysteine have presented a lower mortality and a better evolution in this study. Future prospective studies or randomized clinical trials must confirm the impact of N-acetylcysteine on COVID-19 patients (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Infecções por Coronavirus/mortalidade , Infecções por Coronavirus/terapia , Acetilcisteína/uso terapêutico , Antivirais/uso terapêutico , Mortalidade Hospitalar , Estudos Retrospectivos , Estudos de Coortes , Prognóstico
3.
Fisioterapia (Madr., Ed. impr.) ; 45(4): 217-234, jul.- ago. 2023. tab
Artigo em Espanhol | IBECS | ID: ibc-222306

RESUMO

Introducción La incidencia de obesidad alcanza casi un tercio de la población mundial. En España habrá más de 27 millones de personas con obesidad para 2030, suponiendo una enorme carga socioeconómica, obligando a realizar intervenciones como la cirugía bariátrica (CB) que también tiene sus complicaciones. En los últimos años ha existido un avance de técnicas de fisioterapia respiratoria (FR) por ejemplo, empleando ejercicios respiratorios o utilizando presión positiva (PP). Objetivo Revisar sistemáticamente las intervenciones de FR en CB centrándonos en el tipo de intervención, momento y sus efectos sobre la función pulmonar. Metodología Se realizó la búsqueda en las bases PubMed, CINAHL y PEDro hasta marzo del 2022. Se incluyeron estudios de intervenciones de FR, que midieran la función pulmonar, en contexto pre-posquirúrgico de CB. Se excluyeron los trabajos que no aportaran datos originales, intervención no realizada por fisioterapeutas o que no miden función respiratoria. La calidad metodológica de los estudios se evaluó con la escala PEDro y JBI cheklist for cohort studies. Resultados Fueron incluidos 16 documentos, 20% presentó excelente calidad metodológica y 50% buena. El tamaño muestral varió entre 24 y 148, al igual que la edad (entre 18-60 años) incluso alcanzando 75 años en algún estudio, predominando el género femenino. El tipo de intervenciones (manuales, instrumentales o educacionales), momento de aplicación (pre y posquirúrgicas) y resultados evaluados fueron muy heterogéneos. Conclusiones Existe gran variabilidad de intervenciones de fisioterapia en CB, la mayoría (75%) mejoran la función pulmonar, otras indican falta de eficacia y algunas no indican cambios (AU)


Introduction The incidence of obesity reaches almost a third of the world population. In Spain, there will be more than 27 million people with obesity in 2030. Assuming an enormous socioeconomic burden, forcing interventions such as bariatric surgery, whit their complications. In recent years, there has been an advance in Respiratory Physiotherapy (RP) techniques, for example, using breathing exercises or using positive pressure (PP). Objective To systematically review RP interventions in bariatric surgery, focusing on the type of intervention, timing, and its effects on lung function. Methodology PubMed, CINAHL and PEDro databases were searched until March 2022. RP emergency studies were included, which measured lung function, in the pre-post-surgical context of bariatric surgery. Studies that did not provide original data, intervention not performed by physiotherapists or that did not measure respiratory function were excluded. The methodological quality of studies was evaluated with the PEDro scale and the JBI checklist for cohort studies. Results 16 documents were included, 20% presented excellent methodological quality and 50% good. The sample size varied between 24 and 148 and age (between 18-60 years), even reaching 75 years in some studies, with the female gender predominating. The type of outbreak (manual, instrumental or educational), time of application (pre and post-surgery) and results evaluated were very heterogeneous. Conclusions There is a high variability in physiotherapy interventions used in bariatric surgery, most (75%) improve lung function, others indicate lack of efficacy and some do not indicate changes (AU)


Assuntos
Humanos , Obesidade Mórbida/cirurgia , Cirurgia Bariátrica , Modalidades de Fisioterapia , Cuidados Pós-Operatórios , Exercícios Respiratórios
4.
Rev Clin Esp (Barc) ; 223(8): 479-485, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-37482215

RESUMO

INTRODUCTION AND AIM: N-Acetylcysteine has been proposed for the treatment of COVID-19 thanks to its mucolytic, antioxidant and anti-inflammatory effects. Our aim is to evaluate its effect on patients admitted with COVID-19 in mortality terms. MATERIAL AND METHODS: Retrospective single-center cohort study. All patients admitted to our hospital for COVID-19 from March to April 2020 have been considered. RESULTS: A total of 378 patients were included, being 196 (51.9%) men, with an average age of 73.3±14.5 years. 52.6% (199) received treatment with N-Acetylcysteine. More than 70% presented coughs, fever, and/or dyspnea. The global hospital mortality was 26.7%. A multivariate analysis through logistic regression identified the age of patients [older than 80; OR: 8.4 (CI95%:3-23.4)], a moderate or severe radiologic affectation measured by the RALE score [OR:7.3 (CI95%:3.2-16.9)], the tobacco consumption [OR:2.8 (CI95%:1.3-6.1)] and previous arrhythmia [OR 2.8 (CI95%: 1.3-6.2)] as risk factor that were independently associated with mortality during the admission. The treatment with N-Acetylcysteine was identified as a protective factor [OR: 0.57 (CI95%: 0.31-0.99)]. Asthma also seems to have a certain protective factor although it was not statistically significant in our study [OR: 0.19 (CI95%: 0.03-1.06)]. CONCLUSIONS: Patients with COVID-19 treated with N-acetylcysteine have presented a lower mortality and a better evolution in this study. Future prospective studies or randomized clinical trials must confirm the impact of N-Acetylcysteine on COVID-19 patients.


Assuntos
COVID-19 , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Acetilcisteína/uso terapêutico , Estudos de Coortes , Estudos Retrospectivos , SARS-CoV-2
5.
Musculoskelet Surg ; 105(2): 189-194, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32124329

RESUMO

BACKGROUND: To present the outcomes of arthroscopic electrothermal shrinkage for partial scapholunate (SL) ligament tears, isolated or with associated triangular fibrocartilage complex (TFCC) injuries. METHODS: A prospective study of 20 patients with symptomatic instability of SL ligament (14 of them also with TFCC wrist injuries) treated with arthroscopic electrothermal shrinkage was conducted using a monopolar radiofrequency probe. No patient showed radiologic signs of static dissociation (mean SL interval 2.2 ± 0.6 mm; mean SL angle 41.4° ± 6.7°) before surgery. All patients underwent follow-up at our clinic regularly for an average of 50.6 months (range 29-80 months). RESULTS: The modified Mayo wrist score improved from a mean of 59 ± 17.1 points preoperatively to 88.3 ± 16.2 points at the final follow-up. At the final clinical examination, a painful Watson scaphoid shift test was found in 3 patients (15%). The mean flexion-extension arc was unchanged (132° ± 19°), and mean grip strength improved 12 kg. No patient showed radiologic signs of arthritis or instability after surgery (mean SL interval 1.9 ± 0.7 mm; mean SL angle 42.7° ± 7.3°). Of the 14 patients with combined TFCC injuries, 3 patients continued complaining of ulnar-sided point tenderness. At the end of the follow-up, 80% of the subjects were satisfied or very satisfied. CONCLUSIONS: SL ligament and TFCC electrothermal shrinkage effectively provided pain relief and grip strength increase for most of the patients treated. LEVEL OF EVIDENCE: Level IV.


Assuntos
Fibrocartilagem Triangular , Traumatismos do Punho , Artroscopia , Colágeno , Humanos , Ligamentos Articulares/diagnóstico por imagem , Ligamentos Articulares/cirurgia , Estudos Prospectivos , Estudos Retrospectivos , Resultado do Tratamento , Fibrocartilagem Triangular/diagnóstico por imagem , Fibrocartilagem Triangular/cirurgia , Traumatismos do Punho/diagnóstico por imagem , Traumatismos do Punho/cirurgia
6.
Neurología (Barc., Ed. impr.) ; 35(8): 551-555, oct. 2020. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-202168

RESUMO

INTRODUCCIÓN: Pese a los recientes avances en el manejo agudo del ictus, se aplican terapias de reperfusión a menos de un 10% de los pacientes. Una de las causas es el retraso en la búsqueda de atención médica por el paciente y sus familiares, que analizaremos a continuación. MÉTODOS: Se realizó un estudio observacional, prospectivo, en pacientes consecutivos con ictus o accidente isquémico transitorio. Se recogieron parámetros sociodemográficos y clínicos, y datos sobre el retraso en la decisión, retraso prehospitalario y el tipo de contacto médico seleccionado. Se realizaron análisis descriptivo, bivariante y multivariante para determinar los factores relacionados con la búsqueda de atención médica en los primeros 15minutos. RESULTADOS: Se recogieron 382 pacientes. Un 24,9% decidió solicitar atención médica en los primeros 15 minutos. Lo favorecieron la severidad del evento (OR: 1,08; IC 95%: 1,04-1,13; p < 0,001), estar acompañado de un hijo (OR: 3,44; IC 95%: 1,88-6,27; p < 0,001) y el tratamiento con insulina (OR: 2,89; IC 95%: 1,35-6,20; p = 0,006). Los infartos lacunares (OR: 0,41; IC 95%: 0,17-0,97; p = 0,042), los infartos parciales de circulación anterior (OR: 0,43; IC 95%: 0,22-0,85; p = 0,015) y los cuadros monosintomáticos sin afasia o paresia de miembros (OR: 0,15; IC 95%: 0,033-0,724; p = 0,018) se relacionaron con retrasos mayores de 15 minutos. CONCLUSIONES: La severidad y estar acompañado de un hijo fueron los principales determinantes de una reacción inmediata. Futuras intervenciones deben promocionar una consulta inmediata independientemente de la severidad, así como incidir en un mayor abanico de síntomas


INTRODUCTION: Despite recent advances in the management of acute stroke, fewer than 10% of patients receive reperfusion therapy. One of the main reasons for such a low rate of administration is the delay on the part of patients and their families in seeking medical attention. This study aimed to analyse this delay. METHODS: A prospective observational study was conducted on consecutive stroke or transient ischaemic attack. Data on sociodemographic and clinical parameters, decision delay, pre-hospital delay, and first medical contact were collected. Descriptive, bivariate, and multivariate logistic regression analyses were performed to determine factors associated with seeking medical attention within the first 15minutes of stroke or TIA occurrence. RESULTS: A total of 382 patients were included, 24.9% of whom had a decision delay of 15 minutes or less. Stroke severity (OR 1.08; 95% CI, 1.04-1.13; P < .001), patient's son/daughter witnessing the event (OR 3.44; 95% CI, 1.88-6.27; P < .001), and insulin treatment (OR 2.89; 95% CI, 1.35-6.20; P = .006) were related to an immediate reaction. Lacunar infarcts (OR 0.41; 95% CI, 0.17-0.97; P=.042), partial anterior circulation infarcts (OR 0.43; 95% CI, 0.22-0.85; P = .015), and monosymptomatic events not involving limb paresis or aphasia (OR 0.15; 95% CI, 0.033-0.724; P = .018) favoured delays longer than 15 minutes. CONCLUSIONS: Severity of the event and presence of a son/daughter are the factors most frequently associated with an immediate response to stroke. Future interventions should emphasise the need for an immediate response irrespective of severity and include a wider spectrum of symptoms


Assuntos
Humanos , Ataque Isquêmico Transitório/complicações , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Acidente Vascular Cerebral/complicações , Crianças Adultas/psicologia , Estudos Prospectivos , Fatores de Risco , Fatores de Tempo
7.
Neurologia (Engl Ed) ; 35(8): 551-555, 2020 Oct.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-29279254

RESUMO

INTRODUCTION: Despite recent advances in the management of acute stroke, fewer than 10% of patients receive reperfusion therapy. One of the main reasons for such a low rate of administration is the delay on the part of patients and their families in seeking medical attention. This study aimed to analyse this delay. METHODS: A prospective observational study was conducted on consecutive stroke or transient ischaemic attack. Data on sociodemographic and clinical parameters, decision delay, pre-hospital delay, and first medical contact were collected. Descriptive, bivariate, and multivariate logistic regression analyses were performed to determine factors associated with seeking medical attention within the first 15minutes of stroke or TIA occurrence. RESULTS: A total of 382 patients were included, 24.9% of whom had a decision delay of 15minutes or less. Stroke severity (OR 1.08; 95% CI, 1.04-1.13; P<.001), patient's son/daughter witnessing the event (OR 3.44; 95% CI, 1.88-6.27; P<.001), and insulin treatment (OR 2.89; 95% CI, 1.35-6.20; P=.006) were related to an immediate reaction. Lacunar infarcts (OR 0.41; 95% CI, 0.17-0.97; P=.042), partial anterior circulation infarcts (OR 0.43; 95% CI, 0.22-0.85; P=.015), and monosymptomatic events not involving limb paresis or aphasia (OR 0.15; 95% CI, 0.033-0.724; P=.018) favoured delays longer than 15minutes. CONCLUSIONS: Severity of the event and presence of a son/daughter are the factors most frequently associated with an immediate response to stroke. Future interventions should emphasise the need for an immediate response irrespective of severity and include a wider spectrum of symptoms.


Assuntos
Ataque Isquêmico Transitório/complicações , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Acidente Vascular Cerebral/complicações , Crianças Adultas/psicologia , Humanos , Estudos Prospectivos , Fatores de Risco , Fatores de Tempo
8.
Nutr. clín. diet. hosp ; 40(2): 73-82, 2020. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-198972

RESUMO

INTRODUCCIÓN: La sobrecarga ponderal infantil constituye un importante problema de salud pública mundial. El índice de masa corporal (IMC) es el indicador más empleado. No existe acuerdo internacional sobre los criterios definitorios que se deben emplear en la infancia, lo que ocasiona gran variabilidad de cifras y dificulta su interpretación. OBJETIVO: Estimar la prevalencia de sobrepeso y obesidad de la población escolar del Área Sanitaria de La Mancha-Centro (Comunidad Autónoma de Castilla-La Mancha) aplicando diferentes criterios definitorios y valorar las diferencias encontradas. MATERIAL Y MÉTODOS: Estudio de corte transversal de una muestra representativa de 954 niños de 6 a 12 años. Se calculó la prevalencia de sobrepeso, obesidad y sobrecarga ponderal global, por sexo e intervalo anual, aplicando los criterios más empleados, nacionales (Estudio Transversal Español de Crecimiento 2010 -ETEC 2010-, Orbegozo 1988, Orbegozo 2004) e internacionales (Organización Mundial de la Salud - OMS-, International Obesity Task Force -IOTF-). RESULTADOS: La prevalencia global de sobrepeso, obesidad y sobrecarga ponderal fue, respectivamente, 25,4%, 21,1%, 46,5% con el criterio de OMS; 26,3%, 11,5%, 37,8% con IOTF; 9,8%, 14,8%, 24,6% con Orbegozo 1988; 10,9%, 15,4%, 26,3% con Orbegozo 2004; y 15,5%, 8,6%, 24,1% con ETEC 2010. Las mujeres presentaron prevalencias más elevadas de sobrepeso y obesidad que los varones, observándose diferencias estadísticamente significativas en la sobrecarga ponderal con todos los criterios empleados. CONCLUSIONES: Los escolares de La Mancha-Centro presentan prevalencias globales muy elevadas de sobrepeso, obesidad y sobrecarga ponderal, ampliamente variables según el criterio utilizado. Estas cifras son superiores a las de la mayoría de los últimos estudios españoles, nacionales o regionales, y de muchos países de nuestro entorno. Las mujeres muestran valores significativamente más altos que los varones. Sería recomendable unificar a nivel internacional qué puntos de corte utilizar en los estudios de exceso ponderal infantil


INTRODUCTION: Childhood excess weight is an important public health worldwide problem nowadays. Body Mass Index (BMI) is the most used indicator to estimate it. There is no international agreement on the defining criteria to be used in children, which implies great data variability and hinders its interpretation. OBJECTIVE: To estimate the prevalence of overweight and obesity in the schoolchildren of "La Mancha-Centro" Health Area (Castilla-La Mancha, Spain) applying different criteria and to assess the differences found. METHODS: Cross-sectional study of a representative sample of 954 from 6 to 12 years old schoolchildren. Overweight, obesity and excess weight prevalence was calculated by sex and age ranges, applying the most used national (Spanish CrossSectional Growth Study 2010 -SCGS 2010-, Orbegozo 1988, Orbegozo 2004) and international (World Health Organization - WHO-, International Obesity Task Force -IOTF-) criteria. RESULTS: Global prevalence of overweight, obesity and excess weight was, respectively, 25,4%, 21,1%, 46,5% with the WHO criteria; 26,3%, 11,5%, 37,8% following IOTF; 9,8%, 14,8%, 24,6% with Orbegozo 1988; 10,9%, 15,4%, 26,3% according to Orbegozo 2004; and 15,5%, 8,6%, 24,1% with SCGS 2010 cut-offs. Overweight and obesity prevalence was higher in girls than in boys, with significant differences in excess weight by all criteria. CONCLUSIONS: Schoolchildren in La Mancha-Centro display high global prevalence of overweight, obesity and excess weight, which varies a lot according to the applied standard and exceeds prevalence of last Spanish, national or regional, and European studies. Girls achieve higher levels than boys significantly. It would be advisable to unify internationally which cut-off points to use in child excess weight studies


Assuntos
Humanos , Masculino , Feminino , Criança , Sobrepeso/epidemiologia , Obesidade Pediátrica/epidemiologia , Índice de Massa Corporal , Pesos e Medidas Corporais/estatística & dados numéricos , Espanha/epidemiologia , Peso-Estatura , Crescimento , Estudos Transversais
9.
Rev Esp Quimioter ; 31(1): 13-20, 2018 Feb.
Artigo em Espanhol | MEDLINE | ID: mdl-29376622

RESUMO

OBJECTIVE: Urine culture, the gold standard to confirm the presence of urinary tract infection (UTI), is the most requested assay in the microbiology department. Our objective was to determine the diagnostic yield of the UF-Series cytometer as a screening method for UTI. METHODS: All the urine samples sent to the six Microbiology Laboratories participating in a period of 5 working days were analyzed. We collected demographic variables, apart from those variables related to urine samples: source and sample type (midstream, catheterized or nephrostomy urines), collection with/without boric acid, cytometer parameters (leukocyturia, bacteriuria, bacteria morphology and epithelial cells) and urine culture results. ROC curves were plotted to determine predictive capacity of the cytometer. RESULTS: A sample of 2,468 patients with average age of 53 years were processed (ratio women:men 2:1). Urine culture detected 23% of positive urine samples. The predictor variables of UTI were: morphology of bacilli, bacteriuria ≥21 bacteria/µL, age ≥65 years, samples collected in the emergency service and hospitalization and preserving conditions. With 21 bacteria/µL as a cut-off point, we obtained a sensitivity of 93.3% and 94.5% negative predictive value, then reducing the samples to be cultured by 28.9% with 1.6% false negatives. CONCLUSIONS: We consider that the UF-Series is a valid and accurate tool for the detection of UTI. Therefore, it could be used as screening method in the clinical practice prior to the urine culture, reducing culture requirement by approximately 30%, with a low false negative rate.


Assuntos
Citometria de Fluxo/instrumentação , Infecções Urinárias/diagnóstico , Infecções Urinárias/microbiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Bacteriúria/microbiologia , Bacteriúria/urina , Reações Falso-Positivas , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Curva ROC , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Urina/microbiologia , Adulto Jovem
10.
Lett Appl Microbiol ; 66(3): 175-181, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29223137

RESUMO

The new Sysmex UF-1000i analyzer - which incorporates bacteria morphology distinction - allows to automatically screen samples to be cultured at microbiology laboratories. We have evaluated the feasibility and accuracy of Sysmex UF-1000i to screen urinary tract infections (UTIs). A total amount of 2468 urine samples from six Spanish hospitals were analysed. Demographic and clinical data such as age, gender, source and sample type, preserving conditions, cytometer parameters (bacteria, leucocytes and bacteria morphology) as well as urine culture results (gold standard) were recorded. After applying data mining techniques, the variables of age, bacteria count and rod morphology were defined as predictive variables of UTIs. By using the UF-1000i in combination with a predictive algorithm of three decision rules, we could identify 94·9 and 47·4% positive and negative urine samples, respectively, with a negative predictive value of 97 and only 1·17% diagnostic error. This error was reduced down to 0·4% when contaminated samples were excluded. Our results show that flow cytometry parameters together with age, by means of a predictive algorithm model, can be used to screen UTIs. Its implementation would avoid culturing 38% of urine samples, and therefore, would reduce time to diagnosis with a discrete false negative ratio. SIGNIFICANCE AND IMPACT OF THE STUDY: Fluorescent flow cytometry performance has recently spread for urine screening. However, controversy about cytometer results can be drawn from medical literature. This study shows the diagnosis accuracy of Sysmex UF-1000i analyzer by means of a group of decision rules encompassing both demographic variables (age) and cytometer parameters (bacteria, leucocytes and bacteria morphology). After applying the predictive algorithm, the UF-1000i could optimally identify 95% urinary tract infections with high negative predictive value and low diagnostic error. Implementation of UF-1000i would avoid culturing almost 38% of urine samples, thus reducing time to diagnosis, unnecessary antibiotic treatments and consequently improving cost-effectiveness.


Assuntos
Bactérias/isolamento & purificação , Citometria de Fluxo/métodos , Urinálise/métodos , Infecções Urinárias/diagnóstico , Urina/microbiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Algoritmos , Carga Bacteriana , Criança , Pré-Escolar , Feminino , Citometria de Fluxo/instrumentação , Hospitais , Humanos , Lactente , Recém-Nascido , Leucócitos , Masculino , Pessoa de Meia-Idade , Infecções Urinárias/microbiologia , Adulto Jovem
11.
Rev. Esp. Cir. Ortop. Traumatol. (Ed. Impr.) ; 61(2): 88-95, mar.-abr. 2017. tab
Artigo em Espanhol | IBECS | ID: ibc-161095

RESUMO

Objetivo. Describir la actividad ortogeriátrica en ancianos con fractura de cadera en el Hospital Mancha Centro basándonos en las recomendaciones de las principales guías clínicas. Material y método. Estudio prospectivo observacional. Se incluyen todos los pacientes mayores de 65 años ingresados en traumatología con fractura de cadera desde abril de 2015 a diciembre de 2015. El paciente ingresa a cargo de traumatología y se interconsulta a geriatría, que realiza una valoración geriátrica preoperatoria y un seguimiento postoperatorio. Resultados. La estancia media prequirúrgica fue de 48h y la estancia media global de 10,3±8,2 días. Los pacientes que sufrieron delirium (42,1%) evolucionaron peor y se derivaron más a residencias. Se transfundieron el 54,7% de los pacientes a pesar de que el 53,5% recibieron hierro intravenoso y/u oral en el postoperatorio. Al alta se pautó calcio y vitamina D al 79% de los pacientes. Fueron valorados por rehabilitación el 36% de los pacientes, recuperando su situación funcional previa el 4,8% y parcialmente el 16,7%. Al alta, un 55% de los pacientes volvieron a su domicilio y un 22% fueron derivados a estancias temporales. Discusión. En este artículo se detalla el manejo de los principales problemas clínicos en nuestro hospital en ancianos con fractura de cadera basándonos en las recomendaciones de las principales guías y resultados de publicaciones al respecto. Conclusiones. En nuestro hospital se siguen las recomendaciones de las guías. Aspectos a mejorar son el manejo de la anemia durante el ingreso y la rehabilitación (AU)


Aim. To describe the orthogeriatric activity in the elderly with hip fractures in the Hospital Mancha Centro, based on the recommendations of the main guidelines. Material and method. Observational prospective study, comprising all patients over 65 years of age admitted to the Traumatology Unit with a hip fracture between April 2015 and December 2015. Patients were admitted under the care of the Traumatology Unit with cross-consultation carried out with the Geriatrics Department, which then carried out a pre-operative geriatric assessment and the post-operative follow-ups. Results. The mean pre-surgery waiting time was 48h and the overall time in hospital was 10.3±8.2 days. Patients who suffered from delirium (42.1%) did not improve as well, and were referred to nursing homes. Blood transfusions were received by 54.7% of the patients, despite 53.5% of them having received intravenous and/or oral iron after the surgery. Treatment with calcium and vitamin D was prescribed in 79% of the patients on discharge. The Rehabilitation Unit assessed 36% of the patients, with 4.8% fully, and 16.7% partially recovering their prior functional status. Upon discharge, 55% of the patients returned to their homes, and 22% were referred to short-term assisted living facilities. Discussion. This article describes how the main clinical problems are handled in the elderly with hip fractures in our hospital, based on recommendations of the main guidelines and publications. Conclusions. Our hospital follows the recommended guidelines. Aspects for improvement include the management of anaemia during admission and rehabilitation (AU)


Assuntos
Humanos , Masculino , Feminino , Idoso , Idoso de 80 Anos ou mais , Hospitais Gerais/métodos , Hospitais Gerais/organização & administração , Hospitais Gerais/normas , Fraturas do Quadril/epidemiologia , Anemia/complicações , Assistência Integral à Saúde/tendências , Idoso Fragilizado/estatística & dados numéricos , Procedimentos Ortopédicos/métodos , Procedimentos Ortopédicos/estatística & dados numéricos , Estudos Prospectivos , Ferro/uso terapêutico , Cálcio/uso terapêutico , Vitamina D/uso terapêutico , Comorbidade , Polifarmacologia
12.
Musculoskelet Surg ; 101(2): 167-172, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28168637

RESUMO

BACKGROUND: This study aims to illustrate the results of percutaneous forefoot surgery (PFS) for correction of hallux valgus. MATERIALS AND METHODS: A prospective study of 108 patients, with hallux valgus deformity, who underwent PFS was conducted. The minimum clinical and radiological follow-up was two years (mean 57.3 months, range 22-112). RESULTS: Preoperative mean visual analog scale was 6.3 ± 1.5 points, and AOFAS scores were 50.6 ± 11 points. At the last follow-up, both scores improved to 1.9 ± 2.4 points and 85.9 ± 1.83 points, respectively. Mean hallux valgus angle changed from 34.3° ± 9.3° preoperatively to 22.5° ± 11.1° at follow-up. At follow-up, 76.5% of the subjects were satisfied or very satisfied. Recurrence of medial 1st MT head pain happened in 22 cases (16.7%). CONCLUSIONS: PFS, in our study, does not improve the radiological and patient satisfaction rate results compared with conventional procedures. The main advantage is a low postoperative pain level, but with an insufficient HVA correction. LEVEL OF EVIDENCE: II, prospective study.


Assuntos
Hallux Valgus/cirurgia , Osteotomia/métodos , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos , Estudos Prospectivos , Adulto Jovem
13.
Rev Esp Cir Ortop Traumatol ; 61(2): 88-95, 2017.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-28214194

RESUMO

AIM: To describe the orthogeriatric activity in the elderly with hip fractures in the Hospital Mancha Centro, based on the recommendations of the main guidelines. MATERIAL AND METHOD: Observational prospective study, comprising all patients over 65 years of age admitted to the Traumatology Unit with a hip fracture between April 2015 and December 2015. Patients were admitted under the care of the Traumatology Unit with cross-consultation carried out with the Geriatrics Department, which then carried out a pre-operative geriatric assessment and the post-operative follow-ups. RESULTS: The mean pre-surgery waiting time was 48h and the overall time in hospital was 10.3±8.2 days. Patients who suffered from delirium (42.1%) did not improve as well, and were referred to nursing homes. Blood transfusions were received by 54.7% of the patients, despite 53.5% of them having received intravenous and/or oral iron after the surgery. Treatment with calcium and vitamin D was prescribed in 79% of the patients on discharge. The Rehabilitation Unit assessed 36% of the patients, with 4.8% fully, and 16.7% partially recovering their prior functional status. Upon discharge, 55% of the patients returned to their homes, and 22% were referred to short-term assisted living facilities. DISCUSSION: This article describes how the main clinical problems are handled in the elderly with hip fractures in our hospital, based on recommendations of the main guidelines and publications. CONCLUSIONS: Our hospital follows the recommended guidelines. Aspects for improvement include the management of anaemia during admission and rehabilitation.


Assuntos
Fixação de Fratura , Geriatria , Fidelidade a Diretrizes/estatística & dados numéricos , Fraturas do Quadril/cirurgia , Comunicação Interdisciplinar , Padrões de Prática Médica/estatística & dados numéricos , Traumatologia , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Fixação de Fratura/métodos , Fixação de Fratura/normas , Fixação de Fratura/estatística & dados numéricos , Avaliação Geriátrica , Fraturas do Quadril/diagnóstico , Hospitais Gerais , Humanos , Masculino , Assistência Perioperatória/métodos , Assistência Perioperatória/normas , Guias de Prática Clínica como Assunto , Estudos Prospectivos , Espanha , Resultado do Tratamento
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